Biosintesis hormon steroid doc

An iodide transport defect, a result of impaired iodide transport by the NIS protein mechanism, is rare and is reflected in defective iodide transport in the thyroid, salivary gland, and gastric mucosa. 144,145 Some mutations in such patients produce reduced activity, and others completely inactivate NIS by preventing the protein from being transported and inserted into the membrane. With the milder NIS mutations, administration of iodide raises the plasma and intrathyroidal iodide concentration, permitting the synthesis of normal quantities of hormone.

Biosintesis hormon steroid doc

biosintesis hormon steroid doc

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