Desonate was approved by the FDA following two major clinical trials in 2006. Each randomized, double-blind, placebo-controlled study enrolled 582 pediatric patients (between the ages of 3 months and 18 years).  The patient was topically administered the drug or placebo two times a day for four weeks. Using the Investigator’s Global Severity Score (IGSS), the treatment was considered successful if at Week 4 there was at least a two (2) point decrease from the patient’s baseline IGSS. In clinical trial 1, 44% of patients succeeded successful treatment of Desonate versus 14% treated with the placebo. In clinical trial 2, 28% of patients succeeded successful treatment of Desonate versus 6% treated with the placebo.
Unfortunately the medical sites don’t recognize the Extractor’s value in treating spider bites, where they specifically caution against doing any kind of suction treatment. That isn’t surprising since most of their other Brown Recluse advice is wrong too. I wrote the earlier story about the quick, effective treatment by Dexamethasone injected around the bite. Actually, we now reserve that for older more advanced bites. If we get a bite now, we normally know by the delayed burning pain in a few hours. Usually we can see the twin fang marks on the red mound also. We use the Extractor on it, pulling out one or two tiny beads of lymph containing the venom, then put a good dollop of cortisone creme on the spot, cover that with a bandaid, and by morning the bite is history.