It was the ethical questions that were new. Is GH not a wise use of finite healthcare resources, or is the physician’s primary responsibility to the patient? If GH is given to most extremely short children to make them taller, will the definition of “extremely short” simply rise, negating the expected social benefit? If GH is given to short children whose parents can afford it, will shortness become a permanent mark of lower social origins? More of these issues are outlined in the ethics section. Whole meetings were devoted to these questions; pediatric endocrinology had become a specialty with its own bioethics issues.
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One of the great things I have learned from all of this is what true hunger is versus emotional/mental hunger. Too often many of us think our stomachs rumble and we are immediately panicked because we are afraid our blood sugar is going to drop and our muscles are going to vaporize. It just doesn’t happen, at least not in normal healthy people. We are well adapted to fasting, and there are actually benefits such as the repair mode reaction (increased GH/IGF-1 etc..), the neurotransmitter enhancements (bo, and so forth that happen. I still would not suggest anyone doing fasting longer then 24hrs and I prefer the ~16hr (flexible) variant I am using for the best of all worlds. But it takes considerably longer then 24hrs before you really start to get detrimental in terms of health. For example everyone is afraid of metabolic slow down, part of the often touted starvation mode, studies have shown that this doesn’t really happen till after about 72hrs (and it may even increase in the period up to 72hrs). Of course we are all different and under different exercise workloads, stress, and so forth but basically I am saying 16hrs should be np at all for healthy humans.
Human Growth Hormone is an injectable hormone that can be administered subcutaneously or intramuscularly. When injected subcutaneously, HGH carries a bioavailability of approximately seventy-five percent. When injected intramuscularly, HGH carries a bioavailability of approximately sixty-three percent. The mode of administration will also affect the half-life of the Somatropin hormone. When injected subcutaneously, it will carry a half-life of approximately hours. When injected intramuscularly, it will carry a half-life of approximately hours. While this is a rather short half-life regardless of the mode of administration, keep in mind the total effects far outlast these numbers due to the pronounced and significant increases in IGF-1 production that stretch far past the twenty-four hour mark.