Regulation of expression of steroidogenic enzymes in leydig cells

Eukaryotic cells, in contrast, have intracellular organelles that add to their complexity. In eukaryotic cells, the DNA is contained inside the cell’s nucleus where it is transcribed into RNA. The newly-synthesized RNA is then transported out of the nucleus into the cytoplasm where ribosomes translate the RNA into protein. The processes of transcription and translation are physically separated by the nuclear membrane; transcription occurs only within the nucleus, and translation occurs only outside the nucleus within the cytoplasm. The regulation of gene expression can occur at all stages of the process. Regulation may occur when the DNA is uncoiled and loosened from nucleosomes to bind transcription factors (epigenetics), when the RNA is transcribed (transcriptional level), when the RNA is processed and exported to the cytoplasm after it is transcribed (post-transcriptional level), when the RNA is translated into protein (translational level), or after the protein has been made (post-translational level).

As you can see, our genes are not completely in charge of defining our physical characteristics. Instead, they're more like basic instructions for different possibilities of protein products. Other cellular functions get to help decide how our genes are expressed by controlling how much, and how often, our proteins are produced. It makes sense now that two identical twins can turn out looking so different. Because they don't always experience the same environments during their lifetimes, their genes are expressed in different ways due to the processes of gene regulation.

The translation of mRNA can also be controlled by a number of mechanisms, mostly at the level of initiation. Recruitment of the small ribosomal subunit can indeed be modulated by mRNA secondary structure, antisense RNA binding, or protein binding. In both prokaryotes and eukaryotes, a large number of RNA binding proteins exist, which often are directed to their target sequence by the secondary structure of the transcript, which may change depending on certain conditions, such as temperature or presence of a ligand (aptamer). Some transcripts act as ribozymes and self-regulate their expression.

Regulation of expression of steroidogenic enzymes in leydig cells

regulation of expression of steroidogenic enzymes in leydig cells

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regulation of expression of steroidogenic enzymes in leydig cellsregulation of expression of steroidogenic enzymes in leydig cellsregulation of expression of steroidogenic enzymes in leydig cellsregulation of expression of steroidogenic enzymes in leydig cellsregulation of expression of steroidogenic enzymes in leydig cells

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