Athletes, like all others, may have illnesses or conditions that require them to take particular medications. If the medication an athlete is required to take to treat an illness or condition happens to fall under the prohibited list, a therapeutic use exemption may give that athlete the authorization to take the needed medicine. Criteria for granting a therapeutic use exemption are 1.) The athlete would experience significant health problems without taking the prohibited substance or method, 2.) The therapeutic use of the substance would not produce significant enhancement of performance, and 3.) There is no reasonable therapeutic alternative to the use of the otherwise prohibited substance or method. Note hormone replacement therapy (HRT), . supplementing with prescribed testosterone in any form to raise testosterone levels due to natural decreases that occur with aging (even if to just elevate levels to within ‘normal’ ranges), is NOT considered a medicinal exception. Persons using HRT would not be eligible for WPA/NANBF/IPE competition.
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After the double-murder suicide, former wrestler Christopher Nowinski contacted Benoit's father, suggesting that years of trauma to his son's brain may have led to his actions. Tests were conducted on Benoit's brain by Julian Bailes, the head of neurosurgery at West Virginia University, and results showed that "Benoit's brain was so severely damaged it resembled the brain of an 85-year-old Alzheimer's patient." He was reported to have had an advanced form of dementia, similar to the brains of four retired NFL players who had suffered multiple concussions, sank into depression, and harmed themselves or others. Bailes and his colleagues concluded that repeated concussions can lead to dementia, which can contribute to severe behavioral problems.